tag:blogger.com,1999:blog-8174880937451768707.post7519473291503535614..comments2023-10-18T05:54:19.015-07:00Comments on Stronger After Stroke Blog (THE STROKE RECOVERY BLOG): Stroke Survivors Are...Peter G Levinehttp://www.blogger.com/profile/12585356059363005619noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-8174880937451768707.post-13436880329610460872012-02-15T20:18:14.539-08:002012-02-15T20:18:14.539-08:00See, for example, among many other credible links:...See, for example, among many other credible links:Michael Merzenich, PhD (http://keck.ucsf.edu/neurograd/faculty/merzenich.html and http://www.ted.com/talks/michael_merzenich_on_the_elastic_brain.html); and the ample, rigorous and exciting work of V.S. Ramachandran MD, PhD(http://cbc.ucsd.edu/ramabio.html).Billy Ethridgehttps://www.blogger.com/profile/15816168583613213657noreply@blogger.comtag:blogger.com,1999:blog-8174880937451768707.post-29839025346028254072012-01-31T18:00:17.903-08:002012-01-31T18:00:17.903-08:00some more stuff about plasticity :
http://jslhr.a...some more stuff about plasticity :<br /><br />http://jslhr.asha.org/cgi/content/abstract/51/1/S225<br /><br />The study is good because it shows the factors that determines recovery.They used lab rats in the study.Nothing molecular was discussed in the paper.How come no one talks about the importance of nutrition in recovery( whole food and not tabs)?Mikehttps://www.blogger.com/profile/16346073608627020244noreply@blogger.comtag:blogger.com,1999:blog-8174880937451768707.post-39194480561486013092012-01-31T16:55:47.352-08:002012-01-31T16:55:47.352-08:00Dean,
First, I misquoted you what you actually sa...Dean,<br /><br />First, I misquoted you what you actually said was "If we knew the answer to this the recovery of penumbra and bleed damage areas might be able to be repeatable."<br /><br />In terms of migrating neurons, that's not where the most neuroplastic change comes from. Most of the cortical rewiring happens right around the area of infarct, although we've seen brain scans (FMRI)where the rewiring is some distance from the lesion.Peter G Levinehttps://www.blogger.com/profile/13595198575349062833noreply@blogger.comtag:blogger.com,1999:blog-8174880937451768707.post-91166411548573099112012-01-31T16:03:04.026-08:002012-01-31T16:03:04.026-08:00And I think this research hints that brain neurons...And I think this research hints that brain neurons signal for help since the new neurons migrate to the damaged area.<br />http://www.sciencedaily.com/releases/2006/12/061223092924.htm<br />In mice, after a stroke was initiated in a part of the brain located far from the SVZ, the researchers, using a combination of mitotic, genetic, and viral labeling, tracked newly formed neuroblasts (immature brain cells from which mature adult neurons form) as they traveled through healthy brain tissue to the stroke area. Once there, these immature neurons wrapped themselves around the immature vascular cells that were in the process of forming new blood vessels in the damaged area. The neurons were found to arrive at the site within the first two to four weeks after the stroke.<br /><br /><br />Mice only but hey, humans should be tested.<br />Deanoc1deanhttps://www.blogger.com/profile/02302555382262295577noreply@blogger.comtag:blogger.com,1999:blog-8174880937451768707.post-29745220925523310922012-01-30T08:35:12.673-08:002012-01-30T08:35:12.673-08:00Dean,
You are, of course, one of those stroke sur...Dean,<br /><br />You are, of course, one of those stroke survivors whose smarter than I am -- even after their stroke. Which, I think is totally unfair, but I have issues.<br /><br />The brain is plastic. That's enough for most people, but you want to know how exactly why it is plastic. I don't know. I'll keep my eye open for this information... I may have read it and forgotten... and I'll let you know. What you probably do know is that it's not just the neurons but also the glial cells that are active during the plastic process. Prior to very recently glial cells were thought to only be supportive of neurons, not particularly active on their own. But it turns out that they to communicate with each other and are involved in the plastic process. Maybe the answer lies therein.<br /><br />You say "If we knew the answer to this the recovery of a number of bleed damage areas might be able to be repeatable." Stay tuned Dean. I plan to post something on this blog that's very close to what you're suggesting...<br /><br />Buh Buh Baaaaa!Peter G Levinehttps://www.blogger.com/profile/13595198575349062833noreply@blogger.comtag:blogger.com,1999:blog-8174880937451768707.post-48696978652710539092012-01-29T22:21:22.618-08:002012-01-29T22:21:22.618-08:00Okay Peter, I'll ask what should be a simple q...Okay Peter, I'll ask what should be a simple question. Or at least something I would think researchers should focus on before they prove once again that neuroplasticity works. How exactly does a neuron recruit a next door neuron to help with a task? Does it send out a cry/signal for help? Or are good samaritans running around looking for distressed neurons to help? This answer could also possibly explain why new neurons migrate to the damaged area. If we knew the answer to this the recovery of penumbra and bleed damage areas might be able to be repeatable. Heck we could send magnetic nanoparticles with the appropriate drugs to the damaged areas. If we can find the Higgs boson we can find how neurons call for help.<br />Deanoc1deanhttps://www.blogger.com/profile/02302555382262295577noreply@blogger.com